To exert all one's energy and effort; to spare no pains or effort.
为了完成这项具有挑战性的研究项目，团队成员们都殚精毕力，夜以继日地工作。
To complete this challenging research project, the team members all exerted their utmost energy and effort, working day and night.
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To exert all one's energy and effort; to spare no pains or effort.