To work assiduously and unceasingly; to persevere in one's efforts tirelessly.
他孜孜不已地研究复杂的数学问题，终于找到了创新的解决方案。
He assiduously and ceaselessly researched complex mathematical problems, eventually finding innovative solutions.
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To work assiduously and unceasingly; to persevere in one's efforts tirelessly.