To be at the end of one's strength and strategies; to have exhausted all one's resources and wits.
面对强大的对手，他感到自己力屈计穷，不知该如何应对。
Facing a formidable opponent, he felt his strength and wits were exhausted, unsure how to respond.
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To be at the end of one's strength and strategies; to have exhausted all one's resources and wits.