To be at one's wits' end; to have exhausted all one's plans and wisdom; to run out of ideas and strategies.
面对这突如其来的难题，他感到计穷智极，不知该如何是好。
Faced with this sudden difficult problem, he felt completely at his wits' end, not knowing what to do.
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To be at one's wits' end; to have exhausted all one's plans and wisdom; to run out of ideas and strategies.