To be unaccustomed to the local climate, water, and food; to suffer from acclimatization sickness; to not adapt to a new environment.
他刚到南方城市，几天后就有些不伏水土，身体感到不适。
He just arrived in the southern city, and after a few days, he felt a bit unaccustomed to the local environment, experiencing some physical discomfort.
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